
General Nutrition Center — Empire Mall
Closed · opens 10 AM⚲
Address5000 Empire Mall, Sioux Falls, SD
Sioux Falls, SD
Sioux Falls, SD
☏
Phone(605) 361-0586
Address, phone number and opening hours may have changed — please confirm with the store before you visit. Data last reviewed: November 2026. Report a problem with this store
About this location
This General Nutrition Center store is inside Empire Mall, at 5000 Empire Mall, Sioux Falls, SD.
Opening hours: Monday–Saturday 10 AM – 9 PM; Sunday 11 AM – 7 PM. Hours can change on holidays, so confirm before you go.
You can call the store at (605) 361-0586, or use the directions button to open the route in your map app.
General Nutrition Center, better known as GNC, is a retailer of vitamins, supplements, protein and sports nutrition products, sold in its own stores and online.
Quick answers
Where is General Nutrition Center in Sioux Falls?
This General Nutrition Center store is at 5000 Empire Mall, Sioux Falls, SD.
What are the opening hours of General Nutrition Center in Sioux Falls?
Opening hours: Monday–Saturday 10 AM – 9 PM; Sunday 11 AM – 7 PM. They may change on holidays.
What is the phone number of General Nutrition Center in Sioux Falls?
You can call the store at (605) 361-0586.